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PLUS: Google’s huge bio breakthrough.
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July 27, 2021
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An Australian teen is getting a ~$15k reward from Doritos for her “boldness and entrepreneurial spirit” after her rare puffy Doritos chip went viral online. The takeaway: Find weirdly shaped snacks and make TikToks of them.
</p>
<p style="font-size: 16px; line-height: 20px; padding-bottom: 10px; margin: 0px;">
Today’s rundown:
</p>
<ul style="font-size: 16px; line-height: 20px; padding-bottom: 10px; padding-left: 12px; margin: 0;">
<li style="font-size: 15px; line-height: 140%; margin: 0 0 0 15px; padding: 0px;">
<strong>
Street smarts:
</strong>
How Lacuna’s “digital twins” help cities manage traffic policy.
</li>
<li style="font-size: 15px; line-height: 140%; margin: 0 0 0 15px; padding: 0px;">
<strong>
Boeing is going:
</strong>
The company is giving space another go.
</li>
<li style="font-size: 15px; line-height: 140%; margin: 0 0 0 15px; padding: 0px;">
<strong>
Proteins get the AI treatment:
</strong>
Google’s DeepMind is mapping them out.
</li>
<li style="font-size: 15px; line-height: 140%; margin: 0 0 0 15px; padding: 0px;">
<strong>
Around the web:
</strong>
Awesome, random stuff for your enjoyment.
</li>
</ul>
<p style="font-size: 16px; line-height: 20px; padding-bottom: 10px; margin: 0px;">
Let’s do it.
</p>
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The big idea
</td>
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</a>
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<h2 style="font-size: 22px; line-height: 26px; font-weight: bold; margin: 10px 0px 5px;">
Lacuna’s digital twin technology is a game-changer for city transportation
</h2>
</td>
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<td class="h2020 ignore-defaults" style="padding: 5px 0px 0px;">
<p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
Uber and Lyft have made our lives easier in many ways, but public officials have a bone to pick.
</p>
<p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
From piles of e-scooters to heavy
<a style="color: #d62829; text-decoration: none; -webkit-text-fill-color: #d62829;">
congestion
</a>
, cities have struggled to adjust to ride-sharing’s impact on physical spaces.
</p>
<p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
<a style="color: #d62829; text-decoration: none; -webkit-text-fill-color: #d62829;">
Lacuna
</a>
, a startup that uses digital twin technology to help cities manage and monetize transit networks, just
<a style="color: #d62829; text-decoration: none; -webkit-text-fill-color: #d62829;">
raised
</a>
$16m to help cities align policy with modern transportation, per
<em>
VentureBeat
</em>
.
</p>
<h4 style="font-size: 17px; height: 100%; letter-spacing: 0px; line-height: 22px; padding-top: 8px; margin: 0px;">
<strong>
WTF is a digital twin?
</strong>
</h4>
<p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
Pretty much exactly what it sounds like: a virtual replication of a real-world entity.
</p>
<p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
The tech has been used for everything from art (think NFTs) to manufacturing plants, but cities may be the ultimate use case. Among the companies in the space:
</p>
<ul style="font-size: 16px; line-height: 20px; padding-bottom: 10px; padding-left: 12px; margin: 0;">
<li style="font-size: 15px; line-height: 140%; margin: 0 0 0 15px; padding: 0px;">
<strong>
Esri offers geographic information systems (GIS) mapping software
</strong>
that uses digital twins to simplify city planning
</li>
<li style="font-size: 15px; line-height: 140%; margin: 0 0 0 15px; padding: 0px;">
<strong>
Optibus offers AI-powered public transit software
</strong>
that
<a style="color: #d62829; text-decoration: none;">
uses
</a>
digital twins to optimize routes and scheduling
</li>
</ul>
<p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
Lacuna’s software goes beyond planning and route optimization to help cities use data to implement policies.
</p>
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Lacuna is already making a big difference in Los Angeles...
</strong>
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… which isn’t exactly known for its open roads.
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Since implementing the software, the city has crafted 110 digital policies to ensure ride-sharing platforms are aligned with public interests. As a result, one neighborhood saw complaints drop by
<strong>
73%
</strong>
.
</p>
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Lacuna’s software is open source, which means cities can learn from each other -- so it’s only a matter of time before digital twins come to a city near you.
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SNIPPETS
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Parking Profits:
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Parking startups are
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thriving
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as America avoids public transit and returns to the road.
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Hip-Hop Is Decentralized:
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Inside
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rap music’s crypto bubble.
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Conferences Are Back:
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Cvent, which makes tech to help companies manage conferences, is
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going
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public via SPAC.
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Helmet Therapy
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: In a trial run, a magnetic helmet successfully
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shrunk
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a deadly tumor.
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Tesla’s big quarter:
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The EV maker reported Q2 2021 results on Monday, with net income topping
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$1B
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for the first time ever.
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Space Race
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Boeing’s Starliner (Source: NASA)
</p>
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<h2 style="font-size: 22px; line-height: 26px; font-weight: bold; margin: 10px 0px 5px;">
Boeing tries to revive its space program
</h2>
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We all know the major Space Race players: Bezos, Branson, and Musk.
</p>
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Aerospace firm Boeing will throw its name in the ring this week, with the launch of its Starliner space capsule, per
<a style="color: #d62829; text-decoration: none; -webkit-text-fill-color: #d62829;">
<em>
The Wall Street Journal
</em>
</a>
.
</p>
<p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
If successful, the mission will bring cargo to the International Space Station (ISS).
</p>
<h4 style="font-size: 17px; height: 100%; letter-spacing: 0px; line-height: 22px; padding-top: 8px; margin: 0px;">
<strong>
The launch is a do-over
</strong>
</h4>
<p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
Boeing’s previous space attempt in December 2019 failed due to a software error. At the time, Boeing was reeling from 2 fatal
<a style="color: #d62829; text-decoration: none; -webkit-text-fill-color: #d62829;">
crashes
</a>
(October 2018, March 2019) of its 737 Max commercial plane.
</p>
<p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
With Boeing’s engineering culture already in question, the dud Starliner launch only put the company into further disarray.
</p>
<h4 style="font-size: 17px; height: 100%; letter-spacing: 0px; line-height: 22px; padding-top: 8px; margin: 0px;">
<strong>
This next go-around is a huge opportunity for Boeing
</strong>
</h4>
<p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
NASA is looking for 2 companies to shuttle cargo and crew to the ISS. It currently relies on SpaceX (Musk) with Blue Origin (Bezos) knocking at the door.
</p>
<p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
Bezos is so serious about winning government contracts that he just
<em>
offered
</em>
NASA up to
<a style="color: #d62829; text-decoration: none; -webkit-text-fill-color: #d62829;">
$2B
</a>
to cover the cost on a separate moon lunar lander project.
</p>
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This June, Boeing CEO Dave Calhoun said, “I hate that the other guy gets talked about more than we do.”
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Can Boeing change the narrative this week?
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AI Doing Things
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<img alt="protein shapes" src="https://inboxflows.com/_/image/https%253A%252F%252Fmedia.sailthru.com%252Fcomposer%252Fimages%252Fsailthru-prod-6ks%252FDeepMind.png/?inbox_flows_img_sig=eyJwYXRoIjoiaHR0cHMlM0ElMkYlMkZtZWRpYS5zYWlsdCJ9:1m8LI8:VqvZa7XiFOzTSuhg8F-MdDQLpAjuUW-qgwE4m3Q2enE" style="height: auto; width: 100%; max-width: 600px;" width="600"/>
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Protein shapes in 3D...tbh, doesn’t really look like chicken (Source: DeepMind)
</p>
</td>
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<tr>
<td>
<h2 style="font-size: 22px; line-height: 26px; font-weight: bold; margin: 10px 0px 5px;">
Google’s AI unit makes a huge biology breakthrough
</h2>
</td>
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<tr>
<td class="h2020 ignore-defaults" style="padding: 5px 0px 0px;">
<p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
Proteins are much more than the chicken in the kale salad you’re eating right now.
</p>
<p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
At the most basic level, they are molecules that influence how bacteria, viruses, and the human body behave.
</p>
<p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
And the key way of understanding how a protein works is by knowing its 3D shape, which dictates how it interacts with other proteins.
</p>
<h4 style="font-size: 17px; height: 100%; letter-spacing: 0px; line-height: 22px; padding-top: 8px; margin: 0px;">
<strong>
A Google subsidiary delivers a breakthrough
</strong>
</h4>
<p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
Last week, DeepMind -- an AI startup acquired by Google for
<a style="color: #d62829; text-decoration: none; -webkit-text-fill-color: #d62829;">
$500m
</a>
in 2014 -- released the predicted shapes of 350k+ proteins, per
<a style="color: #d62829; text-decoration: none; -webkit-text-fill-color: #d62829;">
<em>
The New York Times
</em>
</a>
.
</p>
<p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
This freely available knowledge drop is powered by a DeepMind AI program called AlphaFold that can analyze huge dumps of data and draw insights.
</p>
<p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
In the olden times (pre-2014), the process of identifying a protein’s shape was brutally long: It could take years and required X-rays and microscopes.
</p>
<h4 style="font-size: 17px; height: 100%; letter-spacing: 0px; line-height: 22px; padding-top: 8px; margin: 0px;">
<strong>
What can you do with protein shapes?
</strong>
</h4>
<p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
Per
<em>
NYT
</em>
, the predicted protein shapes has many applications:
</p>
<ul style="font-size: 16px; line-height: 20px; padding-bottom: 10px; padding-left: 12px; margin: 0;">
<li style="font-size: 15px; line-height: 140%; margin: 0 0 0 15px; padding: 0px;">
Understanding disease pathways
</li>
<li style="font-size: 15px; line-height: 140%; margin: 0 0 0 15px; padding: 0px;">
Developing new antibiotics to combat bacteria
</li>
<li style="font-size: 15px; line-height: 140%; margin: 0 0 0 15px; padding: 0px;">
Creating biological tools to break down plastic bottles
</li>
</ul>
<h4 style="font-size: 17px; height: 100%; letter-spacing: 0px; line-height: 22px; padding-top: 8px; margin: 0px;">
<strong>
DeepMind’s accuracy varies…
</strong>
</h4>
<p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
… so the protein prediction still needs to be paired with physical experiments.
</p>
<p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
Still, one professor tells
<em>
NYT
</em>
that the broad protein understanding -- including ~250k new shapes -- is 10 years ahead of schedule.
</p>
<p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
Google has no plans to commercialize the product. Not that it really needs to: The search giant made
<a style="color: #d62829; text-decoration: none; -webkit-text-fill-color: #d62829;">
$147B
</a>
on ads last year… including a ton for chicken kale Caesar salads, we’re sure.
</p>
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<img alt="View on our website" height="30" src="https://inboxflows.com/_/image/https%253A%252F%252Fsailthru-media.s3.amazonaws.com%252Fcomposer%252Fimages%252Fsailthru-prod-6ks%252Fweb.png/?inbox_flows_img_sig=eyJwYXRoIjoiaHR0cHMlM0ElMkYlMkZzYWlsdGhydS1tZSJ9:1m8LI8:InYO4HRE6l0DLrE-3aVhOAgy4nYmjGzp8roRxlTrbgU" width="30"/>
</a>
</td>
</tr>
</tbody>
</table>
</td>
</tr>
</table>
</td>
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</td>
</tr>
<tr>
<td style="padding-bottom: 5px;">
</td>
</tr>
<tr>
<td style="width: 100%;">
<table style="width: 100%;">
<tr>
<td style="color: #da2829; font-size: 16px; font-weight: bold; letter-spacing: 1.5px; text-transform: uppercase; padding: 10px 3px 0px;">
AROUND THE WEB
</td>
</tr>
<tr>
<td class="h2020 ignore-defaults" style="font-size: 15px; line-height: 20px; margin: 0; padding: 15px 0px 8px 3px;">
<p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
<strong>
🎤 Tool:
</strong>
Need some background music for karaoke? This
<a style="color: #d62829; text-decoration: none; -webkit-text-fill-color: #d62829;">
website
</a>
will take any song’s MP3 file and separate out the voice.
</p>
<p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
<strong>
🦜 Beautiful:
</strong>
If you like seeing the words “birds” and “photography” in the same sentence, check out the
<a style="color: #d62829; text-decoration: none; -webkit-text-fill-color: #d62829;">
winners
</a>
of the National Audubon Society’s photo contest.
</p>
<p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
<strong>
🛸 Insane:
</strong>
1.8k drones flew in unison over Tokyo to create a beautiful 3D
<a style="color: #d62829; text-decoration: none; -webkit-text-fill-color: #d62829;">
light display
</a>
during the Olympic opening ceremony.
</p>
<p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
<strong>
🎂 Tradition:
</strong>
This family has a
<a style="color: #d62829; text-decoration: none; -webkit-text-fill-color: #d62829;">
unique tradition
</a>
of tossing birthday cakes up in the air and hoping they land face up.
</p>
<p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
<strong>
🗺️ That’s cool:
</strong>
This detailed “
<a style="color: #d62829; text-decoration: none; -webkit-text-fill-color: #d62829;">
Map of the Internet
</a>
” represents thousands of websites as “countries” and categories like “search engines” and “ecommerce” as regions.
</p>
<p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
<strong>
🗣️ Quote:
</strong>
“For a list of all the ways technology has failed to improve the quality of life, please press 3.” -- Alice Kahn, American writer
</p>
</td>
</tr>
<tr>
<td style="border-bottom-color: #dddddd; border-bottom-style: solid; border-bottom-width: 1px;">
</td>
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<td style="padding-bottom: 5px;">
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<td style="width: 100%;">
<table style="width: 100%;">
<tr>
<td style="color: #D62829; font-size: 16px; font-weight: bold; letter-spacing: 1.5px; text-transform: uppercase; padding: 5px 3px 0px;">
TRENDS
</td>
</tr>
<tr id="image">
<td class="h2020 ignore-defaults" style="padding: 0px 3px;">
<center>
<a style="color: #d62829; text-decoration: none;">
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</a>
</center>
</td>
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<tr id="bottom ad copy">
<td class="h2020 ignore-defaults" style="padding: 0px 3px;">
<h2 style="font-size: 20px; font-weight: 800; letter-spacing: 0px; line-height: 24px; margin: 20px 0 0px;">
<strong>
Quick hits from Trends...
</strong>
</h2>
<p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
In case you missed them, here are some of July’s most popular Trends reports:
</p>
<ul style="font-size: 16px; line-height: 20px; padding-bottom: 10px; padding-left: 12px; margin: 0;">
<li style="font-size: 15px; line-height: 140%; margin: 0 0 0 15px; padding: 0px;">
<strong>
Insights from
</strong>
<a style="color: #d62829; text-decoration: none;">
<strong>
Europe’s fastest-growing companies in 2021
</strong>
</a>
<strong>
:
</strong>
Did you anticipate the battery industry swooping from #30 to #1? Peep this report on businesses that are thriving in spite of COVID.
</li>
<li style="font-size: 15px; line-height: 140%; margin: 0 0 0 15px; padding: 0px;">
<strong>
Don’t miss these
</strong>
<a style="color: #d62829; text-decoration: none;">
<strong>
fresh market flares
</strong>
</a>
<strong>
:
</strong>
The scoop on birth control tech, books making a comeback, and the digital marketplace craze.
</li>
<li style="font-size: 15px; line-height: 140%; margin: 0 0 0 15px; padding: 0px;">
<a style="color: #d62829; text-decoration: none;">
<strong>
3 cybersecurity tips
</strong>
</a>
<strong>
to shield startups from hackers:
</strong>
Data privacy is king, both for you and your consumers. It’s a good time to start using 2FA and company password managers.
</li>
</ul>
<p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
Don’t miss the latest market moves,
<a style="color: #d62829; text-decoration: none; -webkit-text-fill-color: #d62829;">
<strong>
try one week of Trends for just $1.
</strong>
</a>
</p>
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See the reports →
</a>
</td>
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<tr>
<td style="color: #D62829; font-size: 16px; font-weight: bold; letter-spacing: 1.5px; text-transform: uppercase; padding: 0px 0px 10px;">
Meme of the day
</td>
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<tr>
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<img alt="parking meme" src="https://inboxflows.com/_/image/https%253A%252F%252Fmedia.sailthru.com%252Fcomposer%252Fimages%252Fsailthru-prod-6ks%252FParking_Meme.png/?inbox_flows_img_sig=eyJwYXRoIjoiaHR0cHMlM0ElMkYlMkZtZWRpYS5zYWlsdCJ9:1m8LI8:VqvZa7XiFOzTSuhg8F-MdDQLpAjuUW-qgwE4m3Q2enE" style="height: auto; width: 100%; max-width: 600px;" width="600"/>
</td>
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<tr>
<td>
<p style="font-family: Helvetica, sans-serif; color: #5f696c; font-size: 12px; font-style: italic; line-height: 20px; margin: 0px; padding: 8px 5px 10px;">
Just why... (Source: MemeDroid)
</p>
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<tr>
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</td>
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SHARE THE HUSTLE
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<p style="font-size: 16px; line-height: 140%; padding-bottom: 10px; margin: 5px 0px 0px;">
Over the years, we’ve learned…
<em>
secrets.
</em>
</p>
<p style="font-size: 16px; line-height: 140%; padding-bottom: 10px; margin: 5px 0px 0px;">
The business secrets, tips, and tricks that have helped founders go from zero to millions -- and even
<em>
billions
</em>
-- of dollars.
</p>
<p style="font-size: 16px; line-height: 140%; padding-bottom: 10px; margin: 5px 0px 0px;">
Want to see ‘em? Just refer 3 more friends to The Hustle and we’ll send you our curated set of interviews with founders from brands like Zola, AWAY, Vungle, Bonobos, and more.
</p>
<p style="font-size: 16px; line-height: 140%; padding-bottom: 10px; margin: 5px 0px 0px;">
Here’s a message you can use to share with your friends:
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Hey! Do you read The Hustle? It’s the best daily business newsletter out there -- only takes 5 minutes to read and you’ll sound like the smartest person in the room. Sign up here, it’s free:
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<em>
P.S. You can always check your referral count
<a style="color: #d62829; text-decoration: none;">
here
</a>
.
</em>
</p>
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Today's email was brought to you by
<a style="color: #d62829; text-decoration: none;" target="_blank">
Trung Phan
</a>
,
<a style="color: #d62829; text-decoration: none;" target="_blank">
Jacob Cohen
</a>
,
<a style="color: #d62829; text-decoration: none;" target="_blank">
Juliet Bennett Rylah
</a>
,
<a style="color: #d62829; text-decoration: none;" target="_blank">
Rob Litterst
</a>
.
<br/>
Editing by: Zachary “Digital Twin” Crockett.
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