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           <td colspan="2" style="color: #ffffff; font-family: 'Helvetica', sans-serif; font-size: 1px; letter-spacing: 0px; line-height: 120%; padding: 0px;">
            PLUS: Are loyalty programs worth more than airlines?
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                  October 5, 2020
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                  <img alt="The Hustle" src="https://inboxflows.com/_/image/https%253A%252F%252Fthdaily.s3-us-west-1.amazonaws.com%252FThe_Hustle_glow_20200518211036.png/?inbox_flows_img_sig=eyJwYXRoIjoiaHR0cHMlM0ElMkYlMkZ0aGRhaWx5LnMzLSJ9:1kXMGd:5S4JUVhg8Q2Y7ywdfIarq35JmAHAI9gtmVS-P5_puSc" style="width: 250px;" width="250"/>
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                  TOGETHER WITH
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                  <p style="font-size: 16px; line-height: 20px; margin: 0px; padding-bottom: 10px;">
                   President Donald Trump and the First Lady, Melania Trump, tested positive for COVID-19, with cases across the White House rising over the weekend. Echoing the words of candidate Joe Biden and former President Barack Obama, we wish everyone affected a speedy recovery from the illness.
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               The Big Idea
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                <img alt="" src="https://inboxflows.com/_/image/https%253A%252F%252Fthdaily.s3-us-west-1.amazonaws.com%252Fregeneron_20201005011624.gif/?inbox_flows_img_sig=eyJwYXRoIjoiaHR0cHMlM0ElMkYlMkZ0aGRhaWx5LnMzLSJ9:1kXMGd:5S4JUVhg8Q2Y7ywdfIarq35JmAHAI9gtmVS-P5_puSc" style="height: auto; width: 100%;"/>
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               <h2 style="font-size: 22px; font-weight: bold; line-height: 26px; margin: 10px 0px 5px;">
                The billionaire doctor duo behind President Trump’s experimental drug
               </h2>
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               <p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
                There are no treatments approved for COVID-19, but President Trump was given an experimental antibody cocktail late last week, under the
                <a style="-webkit-text-fill-color: #d62829; color: #d62829; text-decoration: none;">
                 FDA
                </a>
                ’s compassionate use clearance.
               </p>
               <p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
                The drug is manufactured by Regeneron, a New York-based company whose CEO has known Mr. Trump for years,
                <a style="-webkit-text-fill-color: #d62829; color: #d62829; text-decoration: none;">
                 <em>
                  The New York Times
                 </em>
                </a>
                reports.
               </p>
               <p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
                “All I can say is that [the White House] asked… and we were happy to oblige,” Dr. Leonard S. Schleifer, Regeneron’s co-founder and CEO, told the
                <em>
                 Times
                </em>
                .
               </p>
               <h4 style="font-size: 17px; height: 100%; letter-spacing: 0px; line-height: 22px; margin: 0px; padding-top: 8px;">
                <strong>
                 A doctor spies a market opportunity
                </strong>
               </h4>
               <p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
                Regeneron’s story starts in 1988.
               </p>
               <p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
                According to
                <a style="-webkit-text-fill-color: #d62829; color: #d62829; text-decoration: none;">
                 <em>
                  Forbes
                 </em>
                </a>
                , Schleifer completed his MD and PhD degrees and was working as a neurology professor at Weill Cornell Medical College when he took an entrepreneurial turn.
               </p>
               <p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
                After seeing the success of biotech firm Genentech, Schleifer convinced venture investors to put up $1m to support his startup that would do research on diseases of the nervous system.
               </p>
               <p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
                Schleifer then went out to convince a partner to join him. That man was George Yancopoulos, another MD/PhD who became Regeneron’s chief scientific officer.
               </p>
               <h4 style="font-size: 17px; height: 100%; letter-spacing: 0px; line-height: 22px; margin: 0px; padding-top: 8px;">
                <strong>
                 A prolific partnership
                </strong>
               </h4>
               <p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
                Schleifer and Yancopoulos actually grew up on the same street in Queens, NY, but had never met.
               </p>
               <p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
                As business partners, Schleifer was the dealmaker who gave Yancopoulos the resources and space to do research… and research he did.
               </p>
               <p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
                <em>
                 Forbes
                </em>
                describes Yancopoulos as one of the “most prolific drug hunters of his generation.”
               </p>
               <h4 style="font-size: 17px; height: 100%; letter-spacing: 0px; line-height: 22px; margin: 0px; padding-top: 8px;">
                <strong>
                 But Regeneron’s first blockbuster drug would take decades
                </strong>
               </h4>
               <p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
                <a style="-webkit-text-fill-color: #d62829; color: #d62829; text-decoration: none;">
                 Eylea
                </a>
                , an injectable eye treatment to prevent macular degeneration (AKA vision impairment), hit markets in the early-2010s.
               </p>
               <p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
                Eylea is now one of the world’s top-selling prescription
                <a style="-webkit-text-fill-color: #d62829; color: #d62829; text-decoration: none;">
                 drugs
                </a>
                and the anchor of Regeneron’s $60B market value.
               </p>
               <p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
                Based on their Regeneron stakes, Shleifer and Yancopoulos are now worth
                <a style="-webkit-text-fill-color: #d62829; color: #d62829; text-decoration: none;">
                 $2.3B
                </a>
                and
                <a style="-webkit-text-fill-color: #d62829; color: #d62829; text-decoration: none;">
                 $1.3B
                </a>
                , respectively.
               </p>
               <h4 style="font-size: 17px; height: 100%; letter-spacing: 0px; line-height: 22px; margin: 0px; padding-top: 8px;">
                <strong>
                 Is the COVID-19 cocktail next?
                </strong>
               </h4>
               <p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
                According to the
                <em>
                 NYT,
                </em>
                Regeneron’s antibody treatment “hastened recovery time” of a small number of volunteers in its ongoing study.
               </p>
               <p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
                Much more testing will have to take place before the FDA deems the cocktail safe for wider use.
               </p>
               <p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
                The success (or failure) of this treatment will define the next chapter for this accomplished doctor duo.
               </p>
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            Snippets
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              <strong>
               Big Tech is taking another (virtual) pilgrimage
              </strong>
              to Washington
              <a style="color: #d62829; text-decoration: none;">
               on October 28
              </a>
              . This time, CEOs will answer questions about Section 230 protections.
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              <strong>
               Twitter is testing a new disinformation-reporting
              </strong>
              feature called “
              <a style="color: #d62829; text-decoration: none;">
               Birdwatch
              </a>
              .” If you see a viral lie? Report it to the Birdwatch queue.
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              <strong>
               The movie business has been so bruised
              </strong>
              that, after reopening this summer, the theater chain Cineworld is considering
              <a style="color: #d62829; text-decoration: none;">
               once again closing its doors
              </a>
              .
             </li>
             <li style="font-size: 15px; line-height: 140%; margin: 0 0 0 15px; padding: 0px;">
              <strong>
               Think Calm, but more erotic
              </strong>
              : The startup Emjoy is leading an
              <a style="color: #d62829; text-decoration: none;">
               audio-based sexual wellness boom
              </a>
              .
             </li>
             <li style="font-size: 15px; line-height: 140%; margin: 0 0 0 15px; padding: 0px;">
              <strong>
               Burger King’s Belgian offshoot
              </strong>
              is rolling out a
              <a style="color: #d62829; text-decoration: none;">
               new ad campaign
              </a>
              to… earn a Michelin star?
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               How loyal are you?
              </td>
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              <td style="padding: 0 0 6px;">
               <a style="color: #d62829; text-decoration: none;">
                <img alt="" src="https://inboxflows.com/_/image/https%253A%252F%252Fthdaily.s3-us-west-1.amazonaws.com%252FAirplane_20201005013840.jpg/?inbox_flows_img_sig=eyJwYXRoIjoiaHR0cHMlM0ElMkYlMkZ0aGRhaWx5LnMzLSJ9:1kXMGd:5S4JUVhg8Q2Y7ywdfIarq35JmAHAI9gtmVS-P5_puSc" style="height: auto; width: 100%;"/>
               </a>
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               <h2 style="font-size: 22px; font-weight: bold; line-height: 26px; margin: 10px 0px 5px;">
                Are airline loyalty programs worth more than the actual airlines?
               </h2>
              </td>
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             <tr>
              <td class="h2020 ignore-defaults" style="padding: 5px 0px 0px;">
               <p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
                Airline loyalty programs -- incentives (like free miles) given to travelers -- are a massive business.
               </p>
               <p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
                The top 100 loyalty programs could be worth as much as
                <a style="-webkit-text-fill-color: #d62829; color: #d62829; text-decoration: none;">
                 $200B
                </a>
                . And during the pandemic, they’ve become a lifeline for ailing airlines.
               </p>
               <p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
                To wit: Delta (SkyMiles) and United (MileagePlus) secured respective loans of
                <a style="-webkit-text-fill-color: #d62829; color: #d62829; text-decoration: none;">
                 $6.5B
                </a>
                and
                <a style="-webkit-text-fill-color: #d62829; color: #d62829; text-decoration: none;">
                 $5B
                </a>
                against their loyalty programs to face off a quarantine cash crunch.
               </p>
               <h4 style="font-size: 17px; height: 100%; letter-spacing: 0px; line-height: 22px; margin: 0px; padding-top: 8px;">
                <strong>
                 Airlines have a ‘negative’ worth without loyalty programs
                </strong>
               </h4>
               <p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
                According to a
                <em>
                 Financial Times
                </em>
                <a style="-webkit-text-fill-color: #d62829; color: #d62829; text-decoration: none;">
                 analysis
                </a>
                , loyalty programs are worth ~$26B to Delta -- more than the airline’s current market value of $20B.
               </p>
               <p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
                The same holds for America Airlines ($24B vs $6.6B) and United ($20B vs $10.5B).
               </p>
               <p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
                Without their loyalty program, tech writer
                <a style="-webkit-text-fill-color: #d62829; color: #d62829; text-decoration: none;">
                 Byrne Hobart
                </a>
                notes, Delta’s physical airline operation (planes, landing slots, brand) is worth less than zero -- in this case, negative $6B.
               </p>
               <h4 style="font-size: 17px; height: 100%; letter-spacing: 0px; line-height: 22px; margin: 0px; padding-top: 8px;">
                <strong>
                 However, the valuation exercise is not that straightforward
                </strong>
               </h4>
               <p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
                As Hobart explains, you can’t just simply separate the loyalty programs from the airlines.
               </p>
               <p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
                Customers are loyal to programs because of the capacity and network of destinations they offer. An airline can’t willy-nilly cut ticketing options because of a belief that loyalty programs hold all the value.
               </p>
               <p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
                It’s a package deal.
               </p>
               <p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
                “An airline without its highly profitable loyalty program is a company that faces high labor costs, volatile fuel prices, and a rapidly changing demand environment,” says Hobart.
               </p>
               <p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
                “With loyalty programs,” he says, “that’s offset by a high-margin, high-growth side business.”
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               <p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
                <em>
                 (You can find more of Hobart’s great analysis at his newsletter,
                </em>
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                  The Diff
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                 )
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               FINE-ISH PRINT:
              </strong>
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               eToro USA LLC; Investments are subject to market risk, including the possible loss of principal.
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               Making Paper
              </td>
             </tr>
             <tr>
              <td style="padding: 0 0 6px;">
               <a style="color: #d62829; text-decoration: none;">
                <img alt="" src="https://inboxflows.com/_/image/https%253A%252F%252Fthdaily.s3-us-west-1.amazonaws.com%252FPhilly_Map_20201005013346.jpg/?inbox_flows_img_sig=eyJwYXRoIjoiaHR0cHMlM0ElMkYlMkZ0aGRhaWx5LnMzLSJ9:1kXMGd:5S4JUVhg8Q2Y7ywdfIarq35JmAHAI9gtmVS-P5_puSc" style="height: auto; width: 100%;"/>
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              </td>
             </tr>
             <tr>
              <td>
               <h2 style="font-size: 22px; font-weight: bold; line-height: 26px; margin: 10px 0px 5px;">
                How a Pennsylvania investor group scored a $15B stake in TikTok’s parent company, Bytedance
               </h2>
              </td>
             </tr>
             <tr>
              <td class="h2020 ignore-defaults" style="padding: 5px 0px 0px;">
               <p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
                Move over Dunder Mifflin, there’s a new corporate top dog in Pennsylvania.
               </p>
               <p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
                According to a report from the
                <a style="-webkit-text-fill-color: #d62829; color: #d62829; text-decoration: none;">
                 <em>
                  Wall Street Journal
                 </em>
                </a>
                , the owners of Susquehanna International Group (SIG) -- a derivatives trading firm based in Bala Cynwyd, PA -- have been sitting on a
                <strong>
                 15% stake
                </strong>
                in ByteDance (TikTok’s China-based holding company) for years.
               </p>
               <h4 style="font-size: 17px; height: 100%; letter-spacing: 0px; line-height: 22px; margin: 0px; padding-top: 8px;">
                <strong>
                 SIG is an option-trading giant
                </strong>
               </h4>
               <p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
                Per the
                <em>
                 WSJ
                </em>
                , SIG was founded in 1987 by Arthur Dantchik and a group of college friends. Today, the privately held firm is responsible for more than
                <strong>
                 1 in 5
                </strong>
                options trades in America.
               </p>
               <p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
                SIG, which has no outside investors, has printed so much cash in the past few decades that the ownership group has aggressively looked for investment opportunities outside of its core business.
               </p>
               <h4 style="font-size: 17px; height: 100%; letter-spacing: 0px; line-height: 22px; margin: 0px; padding-top: 8px;">
                <strong>
                 The investment portfolio is extensive
                </strong>
               </h4>
               <p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
                SIG’s owners started with so-called PIPE deals (the sale of large public equity stakes in a private transaction) in the 1990s.
               </p>
               <p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
                The road to TikTok began in the early 2000s when the firm opened SIG Asia Investments in Shanghai. In total, SIG’s China arm invested a collective
                <strong>
                 $2B
                </strong>
                in 260 companies, including ByteDance.
               </p>
               <p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
                SIG plunked down
                <strong>
                 $5m
                </strong>
                in ByteDance in 2012, the year of the company’s founding. Today, that stake is worth
                <strong>
                 $15B
                </strong>
                -- a casual
                <strong>
                 3000x
                </strong>
                return.
               </p>
               <p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
                That’s more “paper” than Dunder Mifflin has ever made.
               </p>
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                <strong>
                 Fully’s got your back right now -- literally
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               <p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
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                to give to your boss so you can score a sick WFH setup and stop working from your couch (which
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                ruin your back).
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                <strong>
                 Back-Having #2:
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                If your boss doesn’t bite -- or just needs another “proof point to win over the finance department” -- Fully is also
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                 running a huge sale on chairs
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                , which, again, are
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                better for your body.
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                When was the last time someone cared about your back this much?
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               <p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
                We rest our case.
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                ).
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            TRENDS
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            <h2 style="font-size: 20px; font-weight: 800; letter-spacing: 0px; line-height: 24px; margin: 20px 0 0px;">
             <strong>
              A minicorn and unicorn have a baby...
             </strong>
            </h2>
            <p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
             In 2017, when President Emmanuel Macron came to power, the former investment banker vowed to make France “a nation of unicorns.”
            </p>
            <p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
             Just three years later, funding for French tech startups has reached an all-time high of over $4.3B. In a recent Trends report, we cover 6+ French
             <em>
              <strong>
               soonicorns
              </strong>
             </em>
             , AKA Macron’s likely bets to become the country’s next billion-dollar companies.
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              Join Trends today
             </a>
             to get access to the full brief on:
            </p>
            <p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
             🏡 Which industry has seen a 2,297% increase in funding in just 2 years
            </p>
            <p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
             📱 The “super apps” that have swept Europe
            </p>
            <p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
             🛴 The micro-mobility company that leveraged post-COVID trends to raise $93.6M
            </p>
            <p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
             ✈️ How companies are rethinking socially distant tourism
            </p>
            <p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
             📈 The index significantly outpacing the SPX this year, while focusing on social and environmental responsibility
            </p>
            <p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
             🐜 The company trading in petrochemicals for insect castings, to disrupt a $10B market.
            </p>
            <p style="font-size: 15px; line-height: 140%; margin: 5px 0px 10px;">
             Get access to this report and dozens of others, with
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            </p>
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            JOBS
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